— Biologics & cell/gene therapy intelligence

The reference layer for biologics and cell/gene therapy.

Search any biologic. Verify any sponsor. Surface the regulatory pathway, designation history, and competitive context that single-source databases don't carry — built for biotech BD, regulatory affairs, and competitive intelligence teams who need answers, not headlines.

Tocilizumab · 200 mg / 10 mL · InjectionBiologicsIQ verified
ACTEMRA
Genentech (Roche) · FDA approved

⚠ Designation
Breakthrough Therapy — CAR-T cytokine release syndrome (2017)
! AE signal
Serious infections · PRR 3.1 · FAERS 2010–2024
i Pathway
BLA125276 · 351(a) · CBER OBP · cross-listed EMA EMEA/H/C/000955

12
Indications
7
Regulators
A2
Trust tier

Live data fetched from biologics_api.brief()

Biologics tracked
Trials linked
Sponsors profiled
Regulatory status rows
Cross-referenced fromFDA CBERopenFDAEMA EPARCHMPCAT (ATMP)ClinicalTrials.govWHO INNPMDAMHRAHealth Canada BGTDNMPA CDECDSCO BiologicsFAERSEudraVigilance
— Coverage

Built on the largest unified biologics data layer.

Every BLA, every ATMP designation, every confirmatory trial — reconciled across FDA CBER, EMA CAT, PMDA, MHRA, Health Canada BGTD, NMPA, and CDSCO. The numbers update at every build. No stale screenshots.

5K+
Approved biologic BLAs
FDA + EMA + PMDA + MHRA + HC + NMPA + CDSCO
20K+
Pipeline assets
Clinical-stage biologics across modalities
80K+
Biologic trials linked
ClinicalTrials.gov + EU CTR + CTIS
300+
Sponsors canonicalised
Cross-source manufacturer reconciliation
24
Modality codes
mAbs, ADCs, CAR-T, AAV, CRISPR base/prime editing, …
15
Regulatory regimes
Tier-1 global coverage with reviewing-office detail
— External-ID coverage

Linked into the global regulatory graph.

BiologicsIQ products carry external identifiers that connect them across regulators and the global nomenclature graph. Linkage rates below — current build.

BLA number
FDA application number cross-link
98.0 %
INN
WHO recommended international name
94.5 %
EMA product number
EMEA/H/C/* cross-link
71.0 %
NCT ID
ClinicalTrials.gov trial registry
86.4 %
FDA UNII
FDA unique ingredient identifier
82.0 %
ATMP class
EMA CAT advanced therapy classification
100.0 %
FEI / DUNS
FDA + DUNS manufacturer identifiers
64.5 %
MeSH / MedDRA
Indication + adverse-event vocabularies
78.2 %
— Capabilities

Beyond the regulator's database.

The four categories of biologics intelligence that single-source databases don't carry. Cross-cutting, structured, queryable.

Cross-regulator product profiles

One profile per biologic, reconciled across FDA, EMA, PMDA, MHRA, Health Canada, NMPA, and CDSCO. Designation history, classification, regulatory pathway, exclusivity expiry — joined at the product level, not chased across portals.

Confirmatory-trial lifecycle (FDORA)

FDA accelerated approvals tracked from grant through confirmatory-trial readout. Per-product status: planned · enrolling · underway · readout pending · converted to full · failed to confirm · withdrawn by sponsor · withdrawn by FDA.

ATMP + cell/gene depth

EMA CAT classification (GTMP / sCTMP / TEP / combined ATMP), 2025 comparability-guideline era flag, vector serotype, cell source, ex-vivo vs in-vivo, transgene — modality-specific fields competitors collapse into 'gene therapy'.

Source-level provenance

Every gold row walks back through silver lineage, the bronze raw payload, and the adapter run that fetched it. Cite source PDFs in regulatory submissions and BD memos with confidence — no claim is unsourced.

— Every biologic. Every signal.

See the data your BD decision deserves.

Each BiologicsIQ product page bundles regulatory status, designation history, indication-level approvals, confirmatory-trial lifecycle, manufacturing sites, adverse-event signals, and HTA decisions. One page, one source of truth.

  • Regulatory status across FDA, EMA, PMDA, MHRA, HC, NMPA, CDSCO
  • Designation history (Orphan · Breakthrough · RMAT · PRIME · Sakigake · ILAP)
  • Indication-level approvals with conversion-to-full dates
  • Confirmatory-trial lifecycle for accelerated approvals (FDORA)
  • Linked manufacturing sites with FDA inspection status
  • Adverse-event signals with disproportionality scoring
  • HTA outcomes from NICE / ICER / G-BA / HAS / CADTH / PBAC
  • Source attribution for every claim — full provenance walk-back
biologicsiq.ai/product/vyvgart-efgartigimod-alfa/

FcRn antagonist · IgG1 Fc fragment
VYVGART
argenx BV · efgartigimod alfa · BLA761195
FDA designation
Orphan · Generalized myasthenia gravis (2021)
EMA designation
PRIME · CIDP (2024)
Confirmatory trials
3 active · NCT04200456 · NCT05288907 · NCT05983133
5
Indications
6
Regulators
A2
Trust tier
— How it works

Three pieces. One coherent product.

01

Ingest authoritative sources

FDA Drugs@FDA + Purple Book, EMA EPAR + CHMP opinions + CAT register, PMDA approvals + JADER, MHRA + Yellow Card, Health Canada DPD + Vigilance, NMPA CDE, CDSCO Biologics, ClinicalTrials.gov + EU CTR + CTIS, WHO INN + PQ, FAERS + EudraVigilance. Continuous refresh on a 24-hour to 7-day cadence depending on source class.

02

Canonicalise at the drug-substance level

INN-anchored canonical drug substances. Sponsor identity reconciled across DUNS / LEI / FEI / EMA org ID / PMDA MAH ID. Manufacturing sites linked at FDA establishment-ID granularity. Crosswalks at the molecule + sponsor level, never at the brand-name level.

03

Surface the intelligence layer

Regulatory status, designation history, confirmatory-trial lifecycle, ATMP classification, adverse-event signals, HTA outcomes — exposed via REST API and a queryable data product. Not buried in PDFs.

— Built for

People who need answers, not headlines.

Biotech BD / licensing

Sponsor pipeline depth, exclusivity-cliff watch, target competitive landscapes, licensing comp search. When a $500M deal hangs on a regulatory timeline, you get an authoritative answer in under a second.

Regulatory affairs

Confirmatory-trial lifecycle tracking. FDA CBER OTP super-office filings. EMA CAT classification under 2025 comparability guidance. Cite source PDFs in submissions without hunting for them.

Competitive intelligence

Designation grants the same week they happen. Label-change feed. Pharmacovigilance signals from FAERS / EudraVigilance / JADER summarised at the product level. Weekly automated brief.

Market access / HEOR

HTA outcomes from NICE / ICER / G-BA / HAS / CADTH / PBAC linked to products. Pricing observations across regions. Biosimilar competition graph for cliff modelling.

— Methodology

Every claim has a source. Every product has a regulatory anchor.

Tier-A profiles follow a 22-section playbook with explicit regulatory anchoring and source attribution. Safety-critical fields refresh every 60 days. The full operating contract is public.

Tier-A biologic profiles

Class III biologics + ATMPs get a 22-section profile with regulatory anchor, designation lineage, confirmatory-trial chain, and post-market signal.

Source attribution per field

Each fact carries an attribution row — source, retrieval date, reviewer, decay clock. No claim is unsourced.

Trust tiers

Three explicit tiers: unverified (registry-only), AI-reviewed (cross-checked), expert-reviewed (signed off by regulatory affairs).

Refresh cadence

Safety-critical fields: 60 days. Regulatory + designation: weekly. FAERS / vigilance: quarterly. Last refresh shown on every page.

— Early access

BiologicsIQ is in private preview.

We're onboarding biotech BD, regulatory affairs, market access, and competitive intelligence teams in waves. Tell us how you'd use BiologicsIQ and we'll get back within 2 business days.

  • ✓ Verified researchers receive free access
  • ✓ Biotech and pharma reviewed individually
  • ✓ Approval typically within 2 business days
  • ✓ No spam, ever

We review every request manually. Approved users typically hear back within 2 business days.